Tocris/Bay 11-7085/1743/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Bay 11-7085/1743/10/10毫克

Tocris/Bay 11-7085/1743/10/10毫克

商品编号： 1743/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:IrreversIBLeinhibitorofTNF-α-inducedIκBαphosphorylation

AlternativeNames:Bay11-7083

ChemicalName:(2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

IrreversibleinhibitorofTNF-α-stimulatedIκBαphosphorylation(IC₅₀~10μM);leadstodecreasedNF-κBandsubsequentdecreasedexpressionofadhesionmolecules.AlsoreversiblyactivatesMAPkinasesandstimulatesapoptosis.Anti-inflammatoryinvivo.

TechnicalData

M.Wt	249.33
Formula	C₁₃H₁₅NO₂S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	196309-76-9
PubChemID	5353432
InChIKey	VHKZGNPOHPFPER-ONNFQVAWSA-N
Smiles	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	24.93	100
	ethanol	24.93	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight249.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	4.01mL	20.05mL	40.11mL
5mM	0.8mL	4.01mL	8.02mL
10mM	0.4mL	2.01mL	4.01mL
50mM	0.08mL	0.4mL	0.8mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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