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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > ligase > Tocris/湾11-7821/1744/10/10毫克
商品详细Tocris/湾11-7821/1744/10/10毫克
Tocris/湾11-7821/1744/10/10毫克
Tocris/湾11-7821/1744/10/10毫克
商品编号: 1744/10
品牌: Tocris Bioscience
市场价: ¥2780.00
美元价: 1668.00
产地: 美国(厂家直采)
公司:
产品分类: 连接酶
公司分类: ligase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:E2ubiquitin(Ub)conjugatingenzymesinhibitor
AlternativeNames:Bay11-7082
ChemicalName:(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

E2ubiquitin(Ub)conjugatingenzymeinhibitor.InhibitstheconjugationofUbtoarangeofE2enzymes.InhibitsE2enzymemediatedIκBαphosphorylationandindirectlydecreasesNF-κbactivity.AlsoreversIBLyactivatesMAPKsignaling.InducesapoptosisofleukemicTcellandB-celllymphomacelllines.AlsoinhibitsactivationofNLRP3inflammasome.

TechnicalData

M.Wt207.25
FormulaC10H9NO2S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber19542-67-7
PubChemID5353431
InChIKeyDOEWDSDBFRHVAP-KRXBUXKQSA-N
SmilesCC1=CC=C(C=C1)S(=O)(=O)C=CC#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.73100
ethanol5.1825

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight207.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.83mL24.13mL48.25mL
5mM0.97mL4.83mL9.65mL
10mM0.48mL2.41mL4.83mL
50mM0.1mL0.48mL0.97mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet