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商品详细Tocris/Bexarotene/5819/10/10 mg

Tocris/Bexarotene/5819/10/10 mg

商品编号： 5819/10

品牌： Tocris Bioscience

市场价： ¥1500.00

美元价： 900.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveRXRagoNIST

AlternativeNames:LGD1069

ChemicalName:4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoicacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveRXRagonist(EC₅₀valuesare24,25and33nMforRXRβ,RXRγandRXRα,respectively).Exhibits>300-foldselectivityforRXRoverRARreceptors.Inhibitstumorcellinvasionandmigrationinvitro,andinhibitsmetastasisandangiogenesisinmousemodels.AlsopromotesbrownADIpogenicdifferentiationandinducesbrownadipogenicreprogrammingfrommyoblasts.

TechnicalData

M.Wt	348.48
Formula	C₂₄H₂₈O₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	153559-49-0
PubChemID	82146
InChIKey	NAVMQTYZDKMPEU-UHFFFAOYSA-N
Smiles	CC(CCC(C)2C)(C)C1=C2C=C(C)C(C(C3=CC=C(C(O)=O)C=C3)=C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	34.85	100
	ethanol	6.97	20mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight348.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.87mL	14.35mL	28.7mL
5mM	0.57mL	2.87mL	5.74mL
10mM	0.29mL	1.43mL	2.87mL
50mM	0.06mL	0.29mL	0.57mL

ProductDatasheets

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