Tocris/CID 2858522/4246/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/CID 2858522/4246/10/10 mg

Tocris/CID 2858522/4246/10/10 mg

商品编号： 4246/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectivelyinhibitsPKC-inducedNF-κBactivation

ChemicalName:1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]ethanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivelyinhibitsproteinkinaseC(PKC)-inducedactivationoftheNF-κBpathway(IC₅₀<0.1μMforPMA-stimulatedIL-8production).Inhibitsantigenreceptor-stimulatedNF-κBactivationinchroniclymphocyticleukemia(CLL)Bcells.DoesnotinhibitotherNF-κBpathways,includingthatactivatedbytumornecrosisfactor(TNF).

TechnicalData

M.Wt	465.63
Formula	C₂₈H₃₉N₃O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	758679-97-9
PubChemID	2858523
InChIKey	CYCGGKILBWERDJ-UHFFFAOYSA-N
Smiles	OCCCNC2=NC1=CC(C)=C(C)C=C1N2CC(C3=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.31	20
	ethanol	9.31	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight465.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.15mL	10.74mL	21.48mL
5mM	0.43mL	2.15mL	4.3mL
10mM	0.21mL	1.07mL	2.15mL
50mM	0.04mL	0.21mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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