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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/CP 424174/6107/10/10毫克
商品详细Tocris/CP 424174/6107/10/10毫克
Tocris/CP 424174/6107/10/10毫克
Tocris/CP 424174/6107/10/10毫克
商品编号: 6107/10
品牌: Tocris Bioscience
市场价: ¥2500.00
美元价: 1500.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:InhibitorofIL-1βpost-translationalprocessing;indirectlyinhibitsNLRP3
ChemicalName:N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofIL-1βpost-translationalprocessing(IC50=210nM).InhibitstheformationofmatureIL-1β.IndirectlyinhibitsNLRP3.Activeinvivoandorallybioavailable.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt452.99
FormulaC22H29ClN2O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber210825-31-3
PubChemID9911728
InChIKeyYRSBLSHMKVQWHP-UHFFFAOYSA-N
SmilesO=S(C1=CC(C(O)(C)C)=CC=C1)(NC(NC2=C(C(C)C)C=C(Cl)C=C2C(C)C)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.3100
ethanol45.3100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight452.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.21mL11.04mL22.08mL
5mM0.44mL2.21mL4.42mL
10mM0.22mL1.1mL2.21mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet