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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/Calhex 231盐酸盐/4387/50/50 mg
商品详细Tocris/Calhex 231盐酸盐/4387/50/50 mg
Tocris/Calhex 231盐酸盐/4387/50/50 mg
Tocris/Calhex 231盐酸盐/4387/50/50 mg
商品编号: 4387/50
品牌: Tocris Bioscience
市场价: ¥18500.00
美元价: 11100.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Negativeallostericmodulatorofthecalcium-sensingreceptor
ChemicalName:4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Negativeallostericmodulatorofthecalciumsensingreceptor(CaSR).Blocksincreasesin[3H]inositolphosphatelevelselicitedbywild-typehCasRactivation(IC50=0.39μMintransientlytransfectedHEK293cells).

CompoundLibraries

Calhex231hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt443.41
FormulaC25H27ClN2O.HCl
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber652973-93-8
PubChemID11849513
InChIKeyKZPHZSFSFANQIS-GRFVZBLOSA-N
SmilesO=C(C4=CC=C(Cl)C=C4)N[C@@H](CCCC3)[C@H]3N[C@H](C)C1=C2C(C=CC=C2)=CC=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.1750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight443.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.26mL11.28mL22.55mL
5mM0.45mL2.26mL4.51mL
10mM0.23mL1.13mL2.26mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet