Tocris/Ciliobrevin A/4529/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Ciliobrevin A/4529/50/50 mg

Tocris/Ciliobrevin A/4529/50/50 mg

商品编号： 4529/50

品牌： Tocris Bioscience

市场价： ¥14180.00

美元价： 8508.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Hedgehog(Hh)pathwayantagoNIST,inhibitsciliogenesis;alsoinhibitsdynein

AlternativeNames:HPI-4

ChemicalName:2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Hedgehog(Hh)pathwayantagonist;blocksSonichedgehog(Shh)-inducedHhpathwayactivation(IC₅₀=7μM)downstreamofSmo.Perturbsprimaryciliaformation;inhibitscytoplasmicAAA+ATPasedynein-dependentmicrotubuleglidingandATPaseactivity.

TechnicalData

M.Wt	358.18
Formula	C₁₇H₉Cl₂N₃O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	302803-72-1
PubChemID	6883982
InChIKey	SESYPWCSIZUIAS-FOWTUZBSSA-N
Smiles	O=C(C1=CC=CC=C1N2)N/C2=C(C(C3=C(Cl)C=C(Cl)C=C3)=O)C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	35.82	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight358.18.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.79mL	13.96mL	27.92mL
5mM	0.56mL	2.79mL	5.58mL
10mM	0.28mL	1.4mL	2.79mL
50mM	0.06mL	0.28mL	0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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