Tocris/Cyclopamine/1623/1/1 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Cyclopamine/1623/1/1 mg

Tocris/Cyclopamine/1623/1/1 mg

商品编号： 1623/1

品牌： Tocris Bioscience

市场价： ¥3700.00

美元价： 2220.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofHedgehog(Hh)signaling

ChemicalName:(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofhedgehog(Hh)signaling,likelyviadirectinhibitionofSmoothened,theaccessoryproteintotheputativeHhreceptorPatched.Anticancerandteratogenicinvivo.Depletesstem-likecancercellsinglioblastomaandblockstumorengraftment.Canalsobeusedtoinducedifferentiationofhumanembryonicstemcells(hESCs)intohormone-expressingendocrinecells.

TechnicalData

M.Wt	411.63
Formula	C₂₇H₄₁NO₂
Storage	Desiccateat-20°C
Purity	≥97%(HPLC)
CASNumber	4449-51-8
PubChemID	442972
InChIKey	QASFUMOKHFSJGL-LAFRSMQTSA-N
Smiles	O[C@H](C2)CC[C@@]1(C)C2=CC[C@]([C@@]([H])3CC[C@@]54O[C@@](C[C@H](C)CN6)([H])[C@]6([H])[C@H]5C)([H])[C@@]([H])1CC3=[C@@]4C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	ethanol	2.06	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight411.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.43mL	12.15mL	24.29mL
5mM	0.49mL	2.43mL	4.86mL
10mM	0.24mL	1.21mL	2.43mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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