Tocris/Elacridar盐酸盐/4646/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Elacridar盐酸盐/4646/10/10 mg

Tocris/Elacridar盐酸盐/4646/10/10 mg

商品编号： 4646/10

品牌： Tocris Bioscience

市场价： ¥4180.00

美元价： 2508.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:P-gpinhibitor

AlternativeNames:GF120918

ChemicalName:N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

P-glycoprotein(P-gp/ABCG1)inhibitor.BlocksP-gp-mediatedmultidrugresistance(MDR)ofthecytotoxicdrugsdoxorubicin(Cat.No.2252)andvincristine(Cat.No.1257)inCHRC5cells.Alsoinhibitsbreastcancerresistanceprotein(BCRP/ABCG2).Orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline.

TechnicalData

M.Wt	600.1
Formula	C₃₄H₃₃N₃O₅.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	143851-98-3
PubChemID	170320
InChIKey	IQOJZZHRYSSFJM-UHFFFAOYSA-N
Smiles	O=C1C3=C(C(C(NC4=CC=C(CCN5CC(C=C(OC)C(OC)=C6)=C6CC5)C=C4)=O)=CC=C3)NC2=C1C=CC=C2OC.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	12	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight600.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.67mL	8.33mL	16.66mL
5mM	0.33mL	1.67mL	3.33mL
10mM	0.17mL	0.83mL	1.67mL
50mM	0.03mL	0.17mL	0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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