Tocris/Ex 26/5833/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Ex 26/5833/10/10 mg

Tocris/Ex 26/5833/10/10 mg

商品编号： 5833/10

品牌： Tocris Bioscience

市场价： ¥3180.00

美元价： 1908.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveS1P₁receptorantagoNIST

ChemicalName:1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveS1P₁receptorantagonist(IC₅₀=0.93nM).Exhibits>3,000-foldselectivityforS1P₁overS1P₂,S1P₃,S1P₄andS1P₅.InduceslymphocytesequestrationinperipherallymphnodesandupregulatesS1P₁receptorexpression.ReducesdiseaseseverityinmicewithEAE.IncreasesIFN-αproductioninstimulateddendriticcellsinvivo.

CompoundLibraries

Ex26isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	494.98
Formula	C₂₈H₂₈ClFN₂O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1233332-37-0
PubChemID	59393740
InChIKey	YVHNBORUVLWCKF-UHFFFAOYSA-N
Smiles	CC(C1=CC(C)=C(C=C1)Cl)NC2=CC=C(C(C3=CC(C)=C(C(C)=C3)C(NC4(C(O)=O)CC4)=O)=C2)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	49.5	100
	ethanol	49.5	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight494.98.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.02mL	10.1mL	20.2mL
5mM	0.4mL	2.02mL	4.04mL
10mM	0.2mL	1.01mL	2.02mL
50mM	0.04mL	0.2mL	0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

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