Tocris/GNF 7/5607/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/GNF 7/5607/50/50毫克

Tocris/GNF 7/5607/50/50毫克

商品编号： 5607/50

品牌： Tocris Bioscience

市场价： ¥18500.00

美元价： 11100.00

产地：美国(厂家直采)

公司：

产品分类：球蛋白

公司分类： globulin

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Rassignalinginhibitor;inhibitsAck1andGCK

ChemicalName:N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Rassignalinginhibitor;inhibitsAck1andgerminalcenterkinase(GCK).Suppressesproliferation,andinducescellcyclearrestandapoptosisinleukemiacellsharboringNRASmutations.Prolongssurvivalinaleukemiacellxenotransplantationmodelinmice.

CompoundLibraries

GNF7isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	547.53
Formula	C₂₈H₂₄F₃N₇O₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	839706-07-9
PubChemID	11478363
InChIKey	SZNYUUZOQHNEKB-UHFFFAOYSA-N
Smiles	CC1=NC=C(NC2=NC=C(CN(C3=C(C)C=CC(NC(C4=CC(C(F)(F)F)=CC=C4)=O)=C3)C(N5C)=O)C5=N2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	27.38	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight547.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.83mL	9.13mL	18.26mL
5mM	0.37mL	1.83mL	3.65mL
10mM	0.18mL	0.91mL	1.83mL
50mM	0.04mL	0.18mL	0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets