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当前位置: 首页 > 产品中心 > Receptors > Tocris/GPBAR-A/4478/10/10 mg
商品详细Tocris/GPBAR-A/4478/10/10 mg
Tocris/GPBAR-A/4478/10/10 mg
Tocris/GPBAR-A/4478/10/10 mg
商品编号: 4478/10
品牌: Tocris Bioscience
市场价: ¥4380.00
美元价: 2628.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:GPBAreceptor(TGR5)agoNIST
ChemicalName:4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPBAreceptoragonist.UpregulatesGLP-1secretionfromintestinalcultures.IncreasesMQAE-fluorescencesuggestingadecreaseinintracellularchlorideconcentrationingallbladderepithelialcells.

CompoundLibraries

GPBAR-AisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt484.37
FormulaC23H15F7N2O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber877052-79-4
PubChemID11656002
InChIKeyZIXNJVGTAXRKAP-UHFFFAOYSA-N
SmilesO=C(CO3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)CC1=C3N=CC=C1C2=C(F)C=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO48.44100
ethanol9.6920

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight484.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.06mL10.32mL20.65mL
5mM0.41mL2.06mL4.13mL
10mM0.21mL1.03mL2.06mL
50mM0.04mL0.21mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet