Tocris/GRI 977143/4779/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/GRI 977143/4779/10/10毫克

Tocris/GRI 977143/4779/10/10毫克

商品编号： 4779/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveLPA₂receptornon-lipidagoNIST

ChemicalName:2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivelysophosphatidicacid2(LPA₂)receptornon-lipidagonist(EC₅₀=3.3μM).DoesnotactivateotherLPAGPCRsatconcentrationsupto10μM.Antiapoptotic;inhibitsactivationofcaspases3,7,8and9,BaxtranslocationandPARP-1cleavage.ActivatesERK1/2survivalpathway.

TechnicalData

M.Wt	391.44
Formula	C₂₂H₁₇NO₄S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	325850-81-5
PubChemID	3114900
InChIKey	GMVZUCHUOYUMLL-UHFFFAOYSA-N
Smiles	O=C(C2=CC=CC3=CC=CC(C4=O)=C23)N4CCCSC1=CC=CC=C1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	39.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight391.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.55mL	12.77mL	25.55mL
5mM	0.51mL	2.55mL	5.11mL
10mM	0.26mL	1.28mL	2.55mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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