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商品详细Tocris/galetrone/6108/50/50 mg

Tocris/galetrone/6108/50/50 mg

商品编号： 6108/50

品牌： Tocris Bioscience

市场价： ¥11700.00

美元价： 7020.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:CYP17inhibitor;alsoandrogenreceptorantagoNIST

AlternativeNames:TOK-001,VN/124-1

ChemicalName:(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CYP17inhibitor(IC₅₀=300nM)andandrogenreceptorantagonist(IC₅₀=384nMinPC3-ARcells).InhibitsDHT-stimulatedprostatecancercellproliferationinvitro.ExhibitsantitumoractivityinSCIDmicebearingprostatecancerxenografts.

TechnicalData

M.Wt	388.55
Formula	C₂₆H₃₂N₂O
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	851983-85-2
PubChemID	11188409
InChIKey	PAFKTGFSEFKSQG-PAASFTFBSA-N
Smiles	[H][C@@]12CC=C([C@]1(CC[C@]3([C@]2(CC=C4C[C@H](CC[C@]34C)O)[H])[H])C)N5C=NC6=CC=CC=C56

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	19.43	50
	ethanol	19.43	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.87mL	25.74mL
5mM	0.51mL	2.57mL	5.15mL
10mM	0.26mL	1.29mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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