Tocris/HPI 1/3839/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/HPI 1/3839/10/10 mg

Tocris/HPI 1/3839/10/10 mg

商品编号： 3839/10

品牌： Tocris Bioscience

市场价： ¥3500.00

美元价： 2100.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitsHedgehogsignaling

ChemicalName:1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylicacid2-methoxyethylester

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Hedgehog(Hh)signalinginhibitor.InhibitsSonichedgehog(Shh)-,SAG-andGli-inducedHhpathwayactivationinShh-LIGHT2cells(IC₅₀valuesare1.5,1.5,4and6μMforShh-,SAG-,Gli2-andGli1-inducedactivation).AlsoinhibitsHhpathwayactivationinSmoM2-LIGHTcells(IC₅₀=2.5μM);inhibitstheproliferationofcerebellargranuleneuronprecursorsexpressingSmoM2.DoesnotinhibitWntsignaling.

TechnicalData

M.Wt	463.52
Formula	C₂₇H₂₉NO₆
Storage	Storeat-20°C
Purity	≥95%(HPLC)
CASNumber	599150-20-6
PubChemID	2926768
InChIKey	ZXSWZQSYZYMZKS-UHFFFAOYSA-N
Smiles	CC2=C(C(OCCOC)=O)C(C3=CC(O)=CC=C3)C1=C(N2)CC(C4=C(OC)C=CC=C4)CC1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	46.35	100
	ethanol	46.35	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight463.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.16mL	10.79mL	21.57mL
5mM	0.43mL	2.16mL	4.31mL
10mM	0.22mL	1.08mL	2.16mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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