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商品详细Tocris/Harmane/1132/100/100 mg

Tocris/Harmane/1132/100/100 mg

商品编号： 1132/100

品牌： Tocris Bioscience

市场价： ¥1300.00

美元价： 780.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Putativeendogenousimidazolineligand.AlsoMAOinhibitor

AlternativeNames:Harman

ChemicalName:1-Methyl-9H-pyrido[3,4-b]indole

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Proposedastheendogenousligandforimidazolinebindingsites.BindstoI₁-sitesinratkidney(IC₅₀=31nM)andI₂-sites(K_i=49nM).Producesdose-dependenthypotensioninvivothatisreversedbyefaroxan(Cat.No.0792).PotentinhibitorofmonoamineoxidaseAandB(IC₅₀valuesare0.5and5μMrespectively).

TechnicalData

M.Wt	182.22
Formula	C₁₂H₁₀N₂
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	486-84-0
PubChemID	5281404
InChIKey	PSFDQSOCUJVVGF-UHFFFAOYSA-N
Smiles	CC1=NC=CC2=C1NC1=C2C=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	1.82	10
	DMSO	21.87	100
	ethanol	21.87	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight182.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	5.49mL	27.44mL	54.88mL
5mM	1.1mL	5.49mL	10.98mL
10mM	0.55mL	2.74mL	5.49mL
50mM	0.11mL	0.55mL	1.1mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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