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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/盐酸美利嗪/4245/50/50 mg
商品详细Tocris/盐酸美利嗪/4245/50/50 mg
Tocris/盐酸美利嗪/4245/50/50 mg
Tocris/盐酸美利嗪/4245/50/50 mg
商品编号: 4245/50
品牌: Tocris Bioscience
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:HumanpregnaneXreceptoragoNIST;H1antagonist
AlternativeNames:Meclozine
ChemicalName:1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazinedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HumanpregnaneXreceptor(hPXR)agonist;strongeractivatorofhPXRthanratPXR.IncreaseshPXRtargetgeneexpressioninhumanhepatocyteprimarycultures.AlsoactsasahistamineH1receptorantagonist.ConfersneuroprotectioninmodelsofpolyQtoxicity.

CompoundLibraries

MeclizinedihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt463.87
FormulaC25H27ClN2.2HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber1104-22-9
PubChemID64713
InChIKeyVCTHNOIYJIXQLV-UHFFFAOYSA-N
SmilesCC1=CC(CN(CC4)CCN4C(C3=CC=C(Cl)C=C3)C2=CC=CC=C2)=CC=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.1950

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight463.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.16mL10.78mL21.56mL
5mM0.43mL2.16mL4.31mL
10mM0.22mL1.08mL2.16mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet