Tocris/NPS 2143盐酸盐/3626/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NPS 2143盐酸盐/3626/10/10 mg

Tocris/NPS 2143盐酸盐/3626/10/10 mg

商品编号： 3626/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveantagoNISTofthecalcium-sensingreceptor;orallyactivecalcilyticagent

ChemicalName:2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrilehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveCa²⁺-sensingreceptorantagonist.BlocksincreasesincytoplasmicCa²⁺concentrationselicitedbyhumanCa²⁺receptorsexpressedinHEK293cells(IC₅₀=43nM).Alsostimulatesparathyroidhormonesecretionfrombovineparathyroidcells(EC₅₀=41nM).Orallyactivecalcilyticcompound.

CompoundLibraries

NPS2143hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	445.38
Formula	C₂₄H₂₅ClNO₂.HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	324523-20-8
PubChemID	9868131
InChIKey	ZEBNDUQLNGYBNL-VEIFNGETSA-N
Smiles	CC(NC[C@@H](O)COC3=C(C#N)C(Cl)=CC=C3)(C)CC2=CC1=CC=CC=C1C=C2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.54	100
	ethanol	4.45	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight445.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.25mL	11.23mL	22.45mL
5mM	0.45mL	2.25mL	4.49mL
10mM	0.22mL	1.12mL	2.25mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets