Tocris/NVP BHG 712/4405/1/1 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/NVP BHG 712/4405/1/1 mg

Tocris/NVP BHG 712/4405/1/1 mg

商品编号： 4405/1

品牌： Tocris Bioscience

市场价： ¥2100.00

美元价： 1260.00

产地：美国(厂家直采)

公司：

产品分类：激酶

公司分类： kinase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentEphB4kinaseinhibitor

ChemicalName:4-Methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]benzamidetrifluoroacetate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofEphB4kinase;exhibitsselectivityforEphB4overmorethan40otherkinasesinvitro,includingFGFR3.InhibitsEphB4autophosphorylationintransientlytransfectedHEK293cells.AlsoinhibitsVEGF-inducedangiogenesisinvivo;thoughttoinhibitEphB4forwardsignaling.Orallyactive.

TechnicalData

M.Wt	617.5
Formula	C₂₆H₂₀F₃N₇O.CF₃CO₂H
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	940310-85-0
PubChemID	73332408
InChIKey	KCYJGZKWKFCVGC-UHFFFAOYSA-N
Smiles	CN1N=CC2=C1N=C(C4=CC=CN=C4)N=C2NC3=CC(C(NC5=CC=CC(C(F)(F)F)=C5)=O)=CC=C3C.OC(C(F)(F)F)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	24.7	40

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight617.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.62mL	8.1mL	16.19mL
5mM	0.32mL	1.62mL	3.24mL
10mM	0.16mL	0.81mL	1.62mL
50mM	0.03mL	0.16mL	0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

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