Tocris/Narciclasine/3715/1/1毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Narciclasine/3715/1/1毫克

Tocris/Narciclasine/3715/1/1毫克

商品编号： 3715/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：细胞增殖

公司分类： cell_proliferation

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Antiproliferativeagent;slowscellcycleprogression

ChemicalName:(2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Exhibitsantiproliferativeandpro-apoptoticeffectsincarcinomacellsanddisplayscytotoxicactivityagainstapanelof60cancercelllines(meanIC₅₀=47nM).Activitydecreasesrateofcelldivisionandincreasesmitosisdurationinvitro.AlsomodulatestheRho/ROCK/LIMkinase/cofilinpathway;stimulatesRhoAactivationandinducesactinpolymerization.

TechnicalData

M.Wt	307.26
Formula	C₁₄H₁₃NO₇
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	29477-83-6
PubChemID	72376
InChIKey	LZAZURSABQIKGB-AEKGRLRDSA-N
Smiles	OC1=C(C(N[C@]4([H])C3=C[C@H](O)[C@@H](O)[C@H]4O)=O)C3=CC2=C1OCO2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	30.73	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight307.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.25mL	16.27mL	32.55mL
5mM	0.65mL	3.25mL	6.51mL
10mM	0.33mL	1.63mL	3.25mL
50mM	0.07mL	0.33mL	0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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