Tocris/Noscapine盐酸盐/1697/100/100 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Noscapine盐酸盐/1697/100/100 mg

Tocris/Noscapine盐酸盐/1697/100/100 mg

商品编号： 1697/100

品牌： Tocris Bioscience

市场价： ¥1900.00

美元价： 1140.00

产地：美国(厂家直采)

公司：

产品分类：其他试剂

公司分类： Other_reagents

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Tubulininhibitor;inducesapoptosis

ChemicalName:(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Opioidalkaloidwithseveralactions.Bindstotubulin,arrestscellsinmitosisandinducesapoptosis.AntagoNISTatbradykininreceptors(pA₂=6.68),inhibitscarbachol-stimulatedphosphoinositolturnoverandenhancesforskolin-stimulatedcAMPincreasesinCNStissues.ModulatesIKKactivation,suppressingtheNF-κBsignalingpathway.Blocksproliferationofhumanleukemiaandmultiplemyelomacells.Exhibitsanti-inflammatoryactivity.

TechnicalData

M.Wt	449.88
Formula	C₂₂H₂₃NO₇.HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	912-60-7
PubChemID	442329
InChIKey	MFLVZFXCSKVCSH-URBRKQAFSA-N
Smiles	O=C2C1=C(OC)C(OC)=CC=C1[C@]([C@]3([H])N(CCC4=C3C(OC)=C5C(OCO5)=C4)C)([H])O2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	22.49	50
	DMSO	44.99	100
	ethanol	4.5	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight449.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.22mL	11.11mL	22.23mL
5mM	0.44mL	2.22mL	4.45mL
10mM	0.22mL	1.11mL	2.22mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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