Tocris/PF 3084014 hydrobromide/5751/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 3084014 hydrobromide/5751/10/10 mg

Tocris/PF 3084014 hydrobromide/5751/10/10 mg

商品编号： 5751/10

品牌： Tocris Bioscience

市场价： ¥3180.00

美元价： 1908.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentγ-secretaseinhibitor

ChemicalName:(2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]pentanamidedihydrobromide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentγ-secretaseinhibitor(IC₅₀valuesare1.2and6.2nMinwholecellandcell-freeassays,respectively).ReducesAβinbrain,CSFandplasmainmiceandguineapigs.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	651.47
Formula	C₂₇H₄₁F₂N₅O.HBr
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1962925-29-6
PubChemID	121513889
InChIKey	LXEYYZYDWLAIPW-KBVFCZPLSA-N
Smiles	O=C(NC3=CN(C(C)(C)CNCC(C)(C)C)C=N3)[C@H](CCC)N[C@H]2CCC1=CC(F)=CC(F)=C1C2.Br.Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	65.15	100
	water	6.51	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight651.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.53mL	7.67mL	15.35mL
5mM	0.31mL	1.53mL	3.07mL
10mM	0.15mL	0.77mL	1.53mL
50mM	0.03mL	0.15mL	0.31mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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