Tocris/PSC 833/4042/1/1毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PSC 833/4042/1/1毫克

Tocris/PSC 833/4042/1/1毫克

商品编号： 4042/1

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofP-gp-mediatedMDR

AlternativeNames:Valspodar

ChemicalName:6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoicacid]-7-L-valine-cyclosporinA

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

P-glycoprotein(P-gp)modulator;inhibitsP-gp-mediatedmultidrug-resistance(MDR).Reversesresistancetoseveralcytotoxicdrugsincludingmitoxantroneanddoxorubicin(resistancefactorsare2.0and6.5respectively)inhumanMDRcancercelllines.Non-immunosuppressiveanalogofcyclosporinA(Cat.No.1101).

TechnicalData

M.Wt	1214.62
Formula	C₆₃H₁₁₁N₁₁O₁₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	121584-18-7
PubChemID	5281884
InChIKey	YJDYDFNKCBANTM-QCWCSKBGSA-N
Smiles	C[C@H](C)[C@@H](C1=O)NC([C@H](CC(C)C)N(C(CN(C([C@H]([C@H](C)C)NC([C@H]([C@]([C@H](C)C/C=C/C)=O)N(C([C@H]([C@@H](C)C)N(C([C@H](CC(C)C)N(C([C@H](CC(C)C)N(C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N1C)=O)=O)=O)C)=O)C)=O)C)=O)C)=O)=O)C)=O)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.86	4

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1214.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.82mL	4.12mL	8.23mL
5mM	0.16mL	0.82mL	1.65mL
10mM	0.08mL	0.41mL	0.82mL
50mM	0.02mL	0.08mL	0.16mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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