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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > protease > Tocris/PTIQ/4604/10/10 mg
商品详细Tocris/PTIQ/4604/10/10 mg
Tocris/PTIQ/4604/10/10 mg
Tocris/PTIQ/4604/10/10 mg
商品编号: 4604/10
品牌: Tocris Bioscience
市场价: ¥3300.00
美元价: 1980.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白酶类
公司分类: protease
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentMMP-3expressioninhibitor;neuroprotective
ChemicalName:1-(3,4-Dihydro-7-hydroxy-6-methoxy-2(1H)-isoquinolinyl)-1-propanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofMMP-3expression(IC50=60nM);down-regulatesinductionofMMP-3inbothstresseddopaminergiccellsandactivatedmicroglia.AlsosuppressesproinflammatoryresponsesandinhibitsNOproductioninactivatedmicroglia.Attenuatesmotordeficits,preventsneurodegenerationandsuppressesmicroglialactivationinaParkinson'sdiseasemousemodel.Brainpenetrant.

TechnicalData

M.Wt235.28
FormulaC13H17NO3
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber1032822-42-6
PubChemID24812799
InChIKeyBEDYMEDICHGLSE-UHFFFAOYSA-N
SmilesO=C(CC)N2CC1=CC(O)=C(OC)C=C1CC2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.NaOH4.7120
DMSO23.53100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight235.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.25mL21.25mL42.5mL
5mM0.85mL4.25mL8.5mL
10mM0.43mL2.13mL4.25mL
50mM0.09mL0.43mL0.85mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet