Tocris/PX 12/2954/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PX 12/2954/50/50 mg

Tocris/PX 12/2954/50/50 mg

商品编号： 2954/50

品牌： Tocris Bioscience

市场价： ¥10100.00

美元价： 6060.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Thioredoxin-1inhibitor

AlternativeNames:IV-2

ChemicalName:2-[(1-Methylpropyl)dithio]-1H-imidazole

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Thioredoxin-1(Trx-1)inhibitor;irreversIBLyinactivatesTrx-1asasubstrateforreductionbythioredoxinreductase(TR);competitivelyinhibitsthereductionofTrx-1byTR(K_i=30.8μM).AttenuatesexpressionofHIF-1α,VEGFandiNOS(IC₅₀valuesare7.2,10.4and18.1μMrespectively).Exhibitsantitumoractivity;directlyinhibitstubulininvitroanddecreasestumormicrovesseldensityinvivo.

TechnicalData

M.Wt	188.31
Formula	C₇H₁₂N₂S₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	141400-58-0
PubChemID	219104
InChIKey	BPBPYQWMFCTCNG-UHFFFAOYSA-N
Smiles	CC(CC)SSC1=NC=CN1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	18.83	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight188.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	5.31mL	26.55mL	53.1mL
5mM	1.06mL	5.31mL	10.62mL
10mM	0.53mL	2.66mL	5.31mL
50mM	0.11mL	0.53mL	1.06mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

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PreparingStockSolutions

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