Tocris/盐酸吡咯他丁/4763/50/50毫克-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > cell_proliferation > Tocris/盐酸吡咯他丁/4763/50/50毫克

商品详细Tocris/盐酸吡咯他丁/4763/50/50毫克

Tocris/盐酸吡咯他丁/4763/50/50毫克

商品编号： 4763/50

品牌： Tocris Bioscience

市场价： ¥17580.00

美元价： 10548.00

产地：美国(厂家直采)

公司：

产品分类：细胞增殖

公司分类： cell_proliferation

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:StABIlizesG-quadruplexes;inducesDNAdamageandcellcyclearrest

ChemicalName:4-(2-Aminoethoxy)N²,N⁶-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamidepentahydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

BindsandstabilizesG-quadruplexes,inducingDNAdamageandcellcyclearrest(K_d=490nM);targetstheproto-oncogeneSrc,reducingSrcproteinabundanceandSrc-dependentmotilityinhumanbreastcancercells.AlsotargetstelomericG-quadruplexes,inducingtelomerasedysfunction.ActivatestheDNA-dependentproteinkinasecatalyticsunbunit(DNA-PKcs).

TechnicalData

M.Wt	778.94
Formula	C₃₁H₃₂N₈O₅.5HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
PubChemID	78243739
InChIKey	SRIZPFGTXSQRFM-UHFFFAOYSA-N
Smiles	NCCOC1=CC(C(NC2=NC(C=CC=C3)=C3C(OCCN)=C2)=O)=NC(C(NC4=CC(OCCN)=C(C=CC=C5)C5=N4)=O)=C1.Cl.Cl.Cl.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	77.89	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight778.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.28mL	6.42mL	12.84mL
5mM	0.26mL	1.28mL	2.57mL
10mM	0.13mL	0.64mL	1.28mL
50mM	0.03mL	0.13mL	0.26mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets