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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/RU-SKI 43盐酸盐/4886/10/10 mg
商品详细Tocris/RU-SKI 43盐酸盐/4886/10/10 mg
Tocris/RU-SKI 43盐酸盐/4886/10/10 mg
Tocris/RU-SKI 43盐酸盐/4886/10/10 mg
商品编号: 4886/10
品牌: Tocris Bioscience
市场价: ¥3580.00
美元价: 2148.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Hedgehogacyltransferase(Hhat)inhibitor;cellpermeable
ChemicalName:2-((2-Methylbutyl)amino)-1-(4-((3-methylphenoxy)methyl-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanonehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Hedgehogacyltransferase(Hhat)inhibitor(IC50=850nM).InhibitsSonicHedgehogN(ShhN)palmitoylationinvitro.Hasnoeffectonporcupine-inducedfattyacidacylationofWnt39a.Attenuatespancreaticcancercellproliferation.Cellpermeable.

CompoundLibraries

RU-SKI43hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt423.01
FormulaC22H30N2O2S.HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
PubChemID90488982
InChIKeyJBBKLHJLHRGJSQ-UHFFFAOYSA-N
SmilesO=C(CNCC(CC)C)N1CCC3=C(C=CS3)C1COC2=CC(C)=CC=C2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.3100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight423.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.36mL11.82mL23.64mL
5mM0.47mL2.36mL4.73mL
10mM0.24mL1.18mL2.36mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet