Tocris/Ro 61-8048/3254/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Ro 61-8048/3254/50/50毫克

Tocris/Ro 61-8048/3254/50/50毫克

商品编号： 3254/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentkynurenine3-monooxygenase(KMO)inhibitor

ChemicalName:3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandcompetitivekynurenine3-monooxygenase(kynurenine3-hydroxylase;KMO)inhibitor(K_i=4.8nM,IC₅₀=37nM).IncreaseskynurenicacidlevelstoconcentrationsthatantagonizetheglycinesiteofNMDAreceptors.Brainpenetrantandexhibitsantidystonic,anticonvulsantandneuroprotectiveactivities.

CompoundLibraries

Ro61-8048isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	421.45
Formula	C₁₇H₁₅N₃O₆S₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	199666-03-0
PubChemID	5282337
InChIKey	NDPBMCKQJOZAQX-UHFFFAOYSA-N
Smiles	O=S(NC1=NC(C2=CC=CC([N+]([O-])=O)=C2)=CS1)(C3=CC=C(OC)C(OC)=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.15	100
	ethanol	4.21	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight421.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.37mL	11.86mL	23.73mL
5mM	0.47mL	2.37mL	4.75mL
10mM	0.24mL	1.19mL	2.37mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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