Tocris/SR 1001/4868/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SR 1001/4868/50/50毫克

Tocris/SR 1001/4868/50/50毫克

商品编号： 4868/50

品牌： Tocris Bioscience

市场价： ¥15100.00

美元价： 9060.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:RORα/γinverseagoNIST

ChemicalName:N-[4-Methyl-5-[[[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]sulfonyl]-2-thiazolylacetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Retinoicacidreceptor-relatedorphanreceptor(ROR)αandγinverseagonist(K_ivaluesare172and111nMforRORαandRORγrespectively).DemonstratesnoactivityatRORβorLXR.SuppressesT_h17celldifferentiationandcytokineexpressionandreducestheseverityofdiseaseinananimalmodelofmulitplesclerosis.

LicensingInformation

SoldunderlicensefromTheScrippsResearchInstitute.

TechnicalData

M.Wt	477.4
Formula	C₁₅H₁₃F₆N₃O₄S₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1335106-03-0
PubChemID	44241473
InChIKey	OZBSSKGBKHOLGA-UHFFFAOYSA-N
Smiles	CC1=C(S(NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)(=O)=O)SC(NC(C)=O)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.74	100
	ethanol	47.74	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight477.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.09mL	10.47mL	20.95mL
5mM	0.42mL	2.09mL	4.19mL
10mM	0.21mL	1.05mL	2.09mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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