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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/SR 9238/5854/50/50毫克
商品详细Tocris/SR 9238/5854/50/50毫克
Tocris/SR 9238/5854/50/50毫克
Tocris/SR 9238/5854/50/50毫克
商品编号: 5854/50
品牌: Tocris Bioscience
市场价: ¥12580.00
美元价: 7548.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectiveLXRinverseagoNIST
ChemicalName:Ethyl5-[[[[3'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveLXRinverseagonist(IC50valuesare43and214nMforLXRβandLXRα,respectively).SelectivelyinhibitsliverLXRoverperipheralLXR.ExhibitsselectivityforLXRoverapanelof20othernuclearreceptors,includingFXR.Reduceshepaticsteatosisinobesemice.

TechnicalData

M.Wt595.73
FormulaC31H33NO7S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1416153-62-2
PubChemID71478195
InChIKeyHDZWHJYZJWLTAG-UHFFFAOYSA-N
SmilesCCOC(C1=CC=C(O1)CN(S(=O)(C2=C(C=C(C=C2C)C)C)=O)CC3=CC=C(C4=CC(S(C)(=O)=O)=CC=C4)C=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO59.57100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight595.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.68mL8.39mL16.79mL
5mM0.34mL1.68mL3.36mL
10mM0.17mL0.84mL1.68mL
50mM0.03mL0.17mL0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet