Tocris/TC-E 5001/5049/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/TC-E 5001/5049/10/10 mg

Tocris/TC-E 5001/5049/10/10 mg

商品编号： 5049/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类： DNA聚合酶

公司分类： DNA_polymerase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potenttankyraseinhibitor

ChemicalName:3-(4-Methoxyphenyl)-5-[[[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxADIazole

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Dualtankyrase(TNKS)inhibitor(K_dvaluesare79and28nMforTNKS1andTNKS2respectively,IC₅₀=33nMforTNKS2)thatisdevoidofactivityatPARP1andPARP2(IC₅₀>19μM).InhibitsWntsignalingandstABIlizesAxin2levels.

TechnicalData

M.Wt	409.46
Formula	C₂₀H₁₉N₅O₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	865565-29-3
PubChemID	16013184
InChIKey	LQZSHPITKSPDLC-UHFFFAOYSA-N
Smiles	CC1=NN=C(SCC3=NC(C4=CC=C(OC)C=C4)=NO3)N1C2=CC=C(OC)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	40.95	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight409.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.44mL	12.21mL	24.42mL
5mM	0.49mL	2.44mL	4.88mL
10mM	0.24mL	1.22mL	2.44mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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