Tocris/VU 0463271/4719/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/VU 0463271/4719/50/50毫克

Tocris/VU 0463271/4719/50/50毫克

商品编号： 4719/50

品牌： Tocris Bioscience

市场价： ¥13700.00

美元价： 8220.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveKCC2inhibitor

ChemicalName:N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitoroftheneuronalK-Clcotransporter,KCC2(IC₅₀=61nM);displays>100-foldselectivityversustheNa-K-2Clcotransporter1(NKCC1)andnoactivityagainstapanelof68GPCRs,ionchannelsandtransporters.

TechnicalData

M.Wt	382.5
Formula	C₁₉H₁₈N₄OS₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1391737-01-1
PubChemID	70690453
InChIKey	DPONSKCACOZTGN-UHFFFAOYSA-N
Smiles	O=C(N(C4CC4)C3=NC(C)=CS3)CSC(C=C2)=NN=C2C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	19.12	50
	ethanol	3.83	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight382.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.61mL	13.07mL	26.14mL
5mM	0.52mL	2.61mL	5.23mL
10mM	0.26mL	1.31mL	2.61mL
50mM	0.05mL	0.26mL	0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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