Tocris/W 54011/5455/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/W 54011/5455/10/10毫克

Tocris/W 54011/5455/10/10毫克

商品编号： 5455/10

品牌： Tocris Bioscience

市场价： ¥5100.00

美元价： 3060.00

产地：美国(厂家直采)

公司：

产品分类：其他试剂

公司分类： Other_reagents

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinityC5areceptorantagoNIST

ChemicalName:N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityC5areceptorantagonist(K_i=2.2nM).InhibitsC5a-inducedgenerationofreactivesuperoxidespecies,chemotaxisandintracellularCa²⁺mobilizationinhumanneutrophils(IC₅₀valuesare1.6,2.7and3.1nM,respectively).

CompoundLibraries

W54011isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	493.08
Formula	C₃₀H₃₆N₂O₂.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	405098-33-1
PubChemID	5311121
InChIKey	UKBJWRMNGCDKNL-UHFFFAOYSA-N
Smiles	CC(C)C1=CC=C(N(CC2=CC=C(N(C)C)C=C2)C(C3C(C=C(OC)C=C4)=C4CCC3)=O)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	24.65	50
	ethanol	4.93	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight493.08.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.03mL	10.14mL	20.28mL
5mM	0.41mL	2.03mL	4.06mL
10mM	0.2mL	1.01mL	2.03mL
50mM	0.04mL	0.2mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets