Tocris/YM 511/3278/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/YM 511/3278/50/50毫克

Tocris/YM 511/3278/50/50毫克

商品编号： 3278/50

品牌： Tocris Bioscience

市场价： ¥13300.00

美元价： 7980.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentaromatase(CYP19)inhibitor

ChemicalName:4-[[(4-Bromophenyl)methyl]-4H-1,2,4-triazol-4-ylamino]benzonitrile

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactive,potentaromatase(CYP19)inhibitor(IC₅₀valuesare0.4and0.12nMatratovaryandhumanplacentacellsrespectively)thatonlyweaklyinhibitsthesynthesisofothersteroidhormones.Reducesplasmaestrogenlevelsintorangesinducedbyovariectomyandinhibitstestosterone-inducedbreastcancercellgrowthinvitro(IC₅₀=0.13nM).

LicensingInformation

(SoldwiththepermissionofAstellasPharmaInc.)

TechnicalData

M.Wt	354.2
Formula	C₁₆H₁₂BrN₅
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	148869-05-0
PubChemID	177865
InChIKey	GGPPBTSXFROGAE-UHFFFAOYSA-N
Smiles	BrC(C=C3)=CC=C3CN(N2C=NN=C2)C1=CC=C(C#N)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	35.42	100
	ethanol	8.86	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight354.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.82mL	14.12mL	28.23mL
5mM	0.56mL	2.82mL	5.65mL
10mM	0.28mL	1.41mL	2.82mL
50mM	0.06mL	0.28mL	0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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