Tocris/OTX 015/6181/50/50毫克-免疫在线蚂蚁淘旗下平台

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Tocris/OTX 015/6181/50/50毫克

商品编号： 6181/50

品牌： Tocris Bioscience

市场价： ¥23980.00

美元价： 14388.00

产地：美国(厂家直采)

公司：

产品分类：多肽

公司分类： peptides

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:BETbromodomaininhibitor;orallybioavailable

ChemicalName:(6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

BETbromodomaininhibitor(IC₅₀valuesareintherange92-112nM).Inhibitsproliferationandinducesapoptosisofleukemiacelllinesinvitro.DecreasesBRD2,BRD4andc-MYCproteinexpression.Orallybioavailable.

TechnicalData

M.Wt	491.99
Formula	C₂₅H₂₂ClN₅O₂S
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	202590-98-5
PubChemID	9936746
InChIKey	GNMUEVRJHCWKTO-FQEVSTJZSA-N
Smiles	CC1=C(C2=C(N3C(C)=NN=C3[C@@H](N=C2C4=CC=C(C=C4)Cl)CC(NC5=CC=C(C=C5)O)=O)S1)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	49.2	100
	ethanol	9.84	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight491.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.03mL	10.16mL	20.33mL
5mM	0.41mL	2.03mL	4.07mL
10mM	0.2mL	1.02mL	2.03mL
50mM	0.04mL	0.2mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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