Tocris/LDN 214117/6152/50/50毫克-免疫在线蚂蚁淘旗下平台

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Tocris/LDN 214117/6152/50/50毫克

商品编号： 6152/50

品牌： Tocris Bioscience

市场价： ¥15900.00

美元价： 9540.00

产地：美国(厂家直采)

公司：

产品分类：氨基酸

公司分类： aminophenol

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveALK2inhibitor

ChemicalName:1-[4-[6-Methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitoroftypeIbonemorphogenicprotein(BMP)receptorALK2(IC₅₀=24nM).ShowspreferenceforALK1andALK2overALK3and164-foldselectivityforBMP6inhibition(IC₅₀=100nM)overTGF-β1.ExhibitsimprovedkinomeselectivityoverK02288(Cat.No.4986)andlowcytotoxicity.

LicensingInformation

SoldforresearchpurposesunderexclusiveagreementfromTheBrighamandWomen"sHospitalInc.USpatent14/776,302

TechnicalData

M.Wt	419.52
Formula	C₂₅H₂₉N₃O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1627503-67-6
PubChemID	91754554
InChIKey	BHUXVRVMMYAXKN-UHFFFAOYSA-N
Smiles	COC1=CC(C2=C(N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)C)=CC(OC)=C1OC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.95	100
	ethanol	41.95	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.92mL	23.84mL
5mM	0.48mL	2.38mL	4.77mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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SolubilityData

PreparingStockSolutions

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