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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/A 939572/4845/50/50 mg
商品详细Tocris/A 939572/4845/50/50 mg
Tocris/A 939572/4845/50/50 mg
Tocris/A 939572/4845/50/50 mg
商品编号: 4845/50
品牌: Tocris Bioscience
市场价: ¥12580.00
美元价: 7548.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentSCD-1inhibitor
ChemicalName:4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentstearoyl-CoAdesaturase1(SCD1)inhibitor(IC50=0.4nM).SelectiveforSCD1overarangeofkinasesandhERGchannels.InhibitsproliferationofsquamouscellcarcinomaFaDucellsinvitro.Alsoinducescelldeathofundifferentiatedhumanembryonicstemcells(ESCs).Orallybioavailable.

CompoundLibraries

A939572isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt387.86
FormulaC20H22ClN3O3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1032229-3-6
PubChemID24905400
InChIKeyDPYTYQFYDLYWHZ-UHFFFAOYSA-N
SmilesO=C(NC3=CC(C(NC)=O)=CC=C3)N1CCC(OC2=C(Cl)C=CC=C2)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.79100
ethanol3.8810mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.58mL12.89mL25.78mL
5mM0.52mL2.58mL5.16mL
10mM0.26mL1.29mL2.58mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet