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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/A 971432/5766/10/10毫克
商品详细Tocris/A 971432/5766/10/10毫克
Tocris/A 971432/5766/10/10毫克
Tocris/A 971432/5766/10/10毫克
商品编号: 5766/10
品牌: Tocris Bioscience
市场价: ¥2700.00
美元价: 1620.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectiveS1P5agoNIST
ChemicalName:1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveS1P5agonist(EC50valuesare4.1and5.7nMincAMPandGTPγSassays,respectively).Exhibits60-foldselectivityoverS1P1,and>1,600-foldselectivityoverS1P2-4,andapanelof129kinasesand79receptors.Improvesblood-brainbarrierintegrityinvitroandreversesage-relatedcognitivedeclineinvivo.Orallyavailable.

TechnicalData

M.Wt366.24
FormulaC18H17Cl2NO3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber1240308-45-5
PubChemID46872626
InChIKeyWAAWETUDFSIYSD-UHFFFAOYSA-N
SmilesClC1=C(Cl)C=C(COC2=CC=C(CN3CC(C(O)=O)C3)C=C2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl36.62100
1eq.NaOH36.62100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight366.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.73mL13.65mL27.3mL
5mM0.55mL2.73mL5.46mL
10mM0.27mL1.37mL2.73mL
50mM0.05mL0.27mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet