Tocris/A01/5397/50/50毫克-免疫在线蚂蚁淘旗下平台

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Tocris/A01/5397/50/50毫克

商品编号： 5397/50

品牌： Tocris Bioscience

市场价： ¥12580.00

美元价： 7548.00

产地：美国(厂家直采)

公司：

产品分类：连接酶

公司分类： ligase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinitySmurf1inhibitor;enhancesBMPsignaling

ChemicalName:[4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinitySmurf1E3ubiquitinligaseinhibitor(K_d=3.7nM).AttenuatesSmurf1-mediatedSmad1/5degradationandenhancesBMPsignaling.PotentiatesBMP-2-inducedosteoblasticactivityinC2C12myoblastsandMC3T3-E1osteoblastprecursorcells.

TechnicalData

M.Wt	512.93
Formula	C₂₂H₂₀ClF₃N₄O₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1007647-73-5
PubChemID	17555704
InChIKey	QFYLTUDRXBNZFQ-UHFFFAOYSA-N
Smiles	ClC1=C(C(F)(F)F)C=C(S(N2CCN(C(C3=CC=C(N4C(C)=CC=N4)C=C3)=O)CC2)(=O)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	51.29	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight512.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.95mL	9.75mL	19.5mL
5mM	0.39mL	1.95mL	3.9mL
10mM	0.19mL	0.97mL	1.95mL
50mM	0.04mL	0.19mL	0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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