Tocris/17-AAG/1515/1/1毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/17-AAG/1515/1/1毫克

Tocris/17-AAG/1515/1/1毫克

商品编号： 1515/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：白蛋白

公司分类： albumin

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveHsp90inhibitor

AlternativeNames:NSC330507,17-(Allylamino)-17-demethoxygeldanamycin,Tanespimycin

ChemicalName:17-Demethoxy-17-(2-propenylamino)geldanamycin

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofheatshockprotein90(Hsp90)chaperoneactivity,andananalogofgeldanamycin(Cat.No.1368).Subsequentlyinhibitstheactivityofoncogenicproteinssuchasp185^erbB-2(IC₅₀=31nM),N-ras,Ki-rasandc-Akt.Antitumorinvivo.AlsoprotectsneuroProgenitorcellsagainststress-inducedapoptosisatlowconcentrations(10nM)invitro.

TechnicalData

M.Wt	585.7
Formula	C₃₁H₄₃N₃O₈
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	75747-14-7
PubChemID	6440175
InChIKey	AYUNIORJHRXIBJ-HTLBVUBBSA-N
Smiles	O=C1C(NCC=C)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C/C=C(C)/C2=O)C(C(N2)=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	58.57	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight585.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.71mL	8.54mL	17.07mL
5mM	0.34mL	1.71mL	3.41mL
10mM	0.17mL	0.85mL	1.71mL
50mM	0.03mL	0.17mL	0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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