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当前位置: 首页 > 产品中心 > Receptors > Tocris/AMD 3465六氢溴化物/4179/10/10毫克
商品详细Tocris/AMD 3465六氢溴化物/4179/10/10毫克
Tocris/AMD 3465六氢溴化物/4179/10/10毫克
Tocris/AMD 3465六氢溴化物/4179/10/10毫克
商品编号: 4179/10
品牌: Tocris Bioscience
市场价: ¥3980.00
美元价: 2388.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectiveCXCR4antagoNIST
ChemicalName:N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminehexahydrobromide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveCXCR4antagonist;exhibits8-foldhigheraffinitythanAMD3100(Cat.No.3299).InhibitsSDF-1α-ligandbinding(Ki=41.7nM).PotentlyinhibitsHIVcellentryinvitro;causesleukocytosisandmobilizeshaematopoieticstemcellsinvivo.

CompoundLibraries

AMD3465hexahydrobromideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt896.07
FormulaC24H38N6.6HBr
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber185991-07-5
PubChemID9897616
InChIKeyARHBIBDGWDRBJH-UHFFFAOYSA-N
SmilesC1(CN3CCCNCCNCCCNCC3)=CC=C(CNCC2=NC=CC=C2)C=C1.Br.Br.Br.Br.Br.Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.425
water44.850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight896.07.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.12mL5.58mL11.16mL
5mM0.22mL1.12mL2.23mL
10mM0.11mL0.56mL1.12mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet