Tocris/AMG 21629/4330/1/1毫克-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Signal_pathway > Tocris/AMG 21629/4330/1/1毫克

商品详细Tocris/AMG 21629/4330/1/1毫克

Tocris/AMG 21629/4330/1/1毫克

商品编号： 4330/1

品牌： Tocris Bioscience

市场价： ¥6900.00

美元价： 4140.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:PotentandselectiveTRPV1antagoNIST

ChemicalName:3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveTRPV1antagonist.BlocksCa²⁺uptakebyCHOcellsexpressingTRPV1receptors(IC₅₀valuesare0.6and0.8nMforcapsaicin(Cat.No.0462)andacid-inducedCa²⁺uptake,respectively).Exhibits>4000-foldselectivityforTRPV1overotherTRPchannels.Blockscapsaicin-inducedflinchresponseandcauseshyperthermiainrats.Orallyavailableandnon-CNSpenetrant.

TechnicalData

M.Wt	472.42
Formula	C₂₂H₁₉F₃N₆O₃
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	939040-79-6
PubChemID	24858024
InChIKey	TUMYQRZCVIQKOQ-UHFFFAOYSA-N
Smiles	NC(C(N4)=O)=NC(C4=CC=C3)=C3OC1=CC(C2=CC=C(C(F)(F)F)C=C2)=NC(NCCOC)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	23.62	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight472.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.12mL	10.58mL	21.17mL
5mM	0.42mL	2.12mL	4.23mL
10mM	0.21mL	1.06mL	2.12mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets