Tocris/AY 9944二盐酸盐/1639/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AY 9944二盐酸盐/1639/10/10 mg

Tocris/AY 9944二盐酸盐/1639/10/10 mg

商品编号： 1639/10

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofHedgehog(Hh)signaling.InhibitsΔ⁷-dehydrocholesterolreductase

ChemicalName:trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanaminedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofhedgehog(Hh)signaling,possIBLyviaseveralmechanisms.InhibitsΔ⁷-dehydrocholesterolreductase(IC₅₀=13nM),thusreducescholesterolbiosynthesis,andalsoinhibitscholesterolesterification.MayalsodirectlyblockthecellularresponsetoHhproteins.Teratogenicinvivo.

TechnicalData

M.Wt	464.3
Formula	C₂₂H₂₈Cl₂N₂.2HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	366-93-8
PubChemID	9954082
InChIKey	GZFYZYBWLCYBMI-MYZJJQSMSA-N
Smiles	ClC(C=CC=C3)=C3CNC[C@H]1CC[C@H](CNCC2=C(Cl)C=CC=C2)CC1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	2.32	5
	water	23.21	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight464.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.15mL	10.77mL	21.54mL
5mM	0.43mL	2.15mL	4.31mL
10mM	0.22mL	1.08mL	2.15mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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