Tocris/AZ 12080282二盐酸盐/4838/50/50毫克-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Signal_pathway > Tocris/AZ 12080282二盐酸盐/4838/50/50毫克

商品详细Tocris/AZ 12080282二盐酸盐/4838/50/50毫克

Tocris/AZ 12080282二盐酸盐/4838/50/50毫克

商品编号： 4838/50

品牌： Tocris Bioscience

市场价： ¥18100.00

美元价： 10860.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:InhibitorofHedgehog(Hh)signaling

ChemicalName:N-[5-(1H-Imidazol-2-yl)-2-methylphenyl]-4-(2-pyridinylmethoxy)benzamidedihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofHedgehog(Hh)signaling(IC₅₀<0.012μMinafireflyreporterassayagainsttheHhpathway).ShowntodisplacecyclopamineinHeLacellsexpressingSmoothened.Exhibitsselectivityagainstp38α.Orallybioavailable.

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

CompoundLibraries

AZ12080282dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	457.35
Formula	C₂₃H₂₀N₄O₂.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
PubChemID	78243727
InChIKey	CPORFOBFIDPDLZ-UHFFFAOYSA-N
Smiles	CC1=CC=C(C2=NC=CN2)C=C1NC(C3=CC=C(OCC4=CC=CC=N4)C=C3)=O.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.73	100
	water	45.73	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight457.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.19mL	10.93mL	21.87mL
5mM	0.44mL	2.19mL	4.37mL
10mM	0.22mL	1.09mL	2.19mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage: