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商品详细Tocris/Adaptiaquin/5953/50/50 mg

Tocris/Adaptiaquin/5953/50/50 mg

商品编号： 5953/50

品牌： Tocris Bioscience

市场价： ¥11700.00

美元价： 7020.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HIF-prolylhydroxylase-2(PHD2)inhibitor;antioxidant

ChemicalName:7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HIF-prolylhydroxylase-2(PHD2)inhibitor.BlocksglutamateinducedROSproductioninHT-22cells,independentofMnSOD.Exhibitsneuroprotectiveeffectsandenhancesfunctionalrecoveryinrodentintracerebralhemorrhagemodels,viainhibitionofATF4dependentgenes.Brainpenetrant.Alsoantioxidant.

TechnicalData

M.Wt	377.82
Formula	C₂₁H₁₆ClN₃O₂
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	385786-48-1
PubChemID	3740671
InChIKey	KKYHNYRUBSYTCZ-UHFFFAOYSA-N
Smiles	OC1=C(N=CC=C1)NC(C2=C(C3=C(C=C2)C=CC=N3)O)C4=CC=C(C=C4)Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	37.78	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight377.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.65mL	13.23mL	26.47mL
5mM	0.53mL	2.65mL	5.29mL
10mM	0.26mL	1.32mL	2.65mL
50mM	0.05mL	0.26mL	0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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