Biological Activity
High affinity 5-HT1A receptor agonist (Kd = 0.38 nM). 7-Hydroxy-PIPAT maleate (Cat. No. 0719) also available.
Licensing Information
Sold with the permission of the University of Pennsylvania
Technical Data
| M. Wt | 461.3 |
| Formula | C16H22INO.C2H2O4 |
| Storage | Desiccate at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1451210-48-2 |
| PubChem ID | 56972162 |
| InChI Key | XIBSIFOFYWBOAQ-JOKMOOFLSA-N |
| Smiles | [H]OC(=O)C(=O)O[H].CCCN(CC=CI)C1CCC2=CC=CC(O)=C2C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.13 | 100 | |
| ethanol | 37.13 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 461.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.17 mL | 10.84 mL | 21.68 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.34 mL |
| 10 mM | 0.22 mL | 1.08 mL | 2.17 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.43 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Zhuang et al (1993) Synthesis of (R,S)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand. J.Med.Chem. 36 3161 PMID: 8230102
Keywords: 8-Hydroxy-PIPAT oxalate, supplier, High, affinity, 5-HT1A, agonists, Serotonin, Receptors, 5-HT1A, Receptors, Tocris Bioscience
