Biological Activity
Potent and selective CB1 agonist (Ki = 2.2 nM). Displays 325-fold selectivity over CB2 receptors. Active in vivo. Also available in water soluble emulsion (Cat. No. 1781).
Technical Data
| M. Wt | 343.55 |
| Formula | C23H37NO |
| Storage | Store at -20°C |
| CAS Number | 229021-64-1 |
| PubChem ID | 5311007 |
| InChI Key | GLGAUBPACOBAMV-DOFZRALJSA-N |
| Smiles | O=C(NC1CC1)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml) |
Preparing Stock Solutions
The following data is based on the product molecular weight 343.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.91 mL | 14.55 mL | 29.11 mL |
| 5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.91 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Hillard et al (1999) Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 289 1427 PMID: 10336536
Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635 PMID: 10469884
Patel et al (2001) Cannabinoid CB1 receptor agonists produce cerebellar dysfunction in mice. 2001 Symposium on the Cannabinoids, International PMID:
Keywords: ACPA, supplier, Potent, selective, CB1, agonists, Cannabinoids, Receptors, cb1r, Arachidonylcyclopropylamide, CB1, Receptors, Tocris Bioscience
