Biological Activity
Serotonin transporter substrate (Ki = 338 nM). Appetite suppressant.
Technical Data
| M. Wt | 220.14 |
| Formula | C10H14ClN.HCl |
| Storage | Desiccate at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 151-06-4 |
| PubChem ID | 65477 |
| InChI Key | WEJDYJKJPUPMLH-UHFFFAOYSA-N |
| Smiles | ClC1=CC=C(CC(C)(N)C)C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 220.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.54 mL | 22.71 mL | 45.43 mL |
| 5 mM | 0.91 mL | 4.54 mL | 9.09 mL |
| 10 mM | 0.45 mL | 2.27 mL | 4.54 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.91 mL |
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References
References are publications that support the products' biological activity.
Rothman et al (1999) Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation 100 869 PMID: 10458725
Keywords: Chlorphentermine hydrochloride, supplier, Potent, serotonin, transporters, substrates, 5HT, appetite, suppressant., 5-HT, Transporters, Tocris Bioscience
