BiologicalActivity
IndirectlyagonizesSEROtoninreceptorsviainhibitionof5-HTre-uptakeandstimulationof5-HTrelease.Anorecticagent;decreasesgrowthhormone,insulin,leptin,fatmass,leanmassandincreasesghrelinindiet-switcheddiet-inducedobesemice.
TechnicalData
| M.Wt | 267.72 |
| Formula | C12H16F3N.HCl |
| Storage | DesiccateatRT |
| CASNumber | 3239-45-0 |
| PubChemID | 66264 |
| InChIKey | ZXKXJHAOUFHNAS-FVGYRXGTSA-N |
| Smiles | C[C@H](NCC)CC1=CC=CC(C(F)(F)F)=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.77 | 100 | |
| water | 26.77 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight267.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.74mL | 18.68mL | 37.35mL |
| 5mM | 0.75mL | 3.74mL | 7.47mL |
| 10mM | 0.37mL | 1.87mL | 3.74mL |
| 50mM | 0.07mL | 0.37mL | 0.75mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.