BiologicalActivity
EndogenousagonistfortheGPR55andCB1receptors(EC50valuesare10and37nMrespectively)thatdisplaysselectivityoverCB2receptors(Kivaluesare21.2nMand>3mMatCB1andCB2respectively).Causessedation,hypothermia,intestinalimmobilityandmildantinociceptioninvivo.AttenuatessensoryneurotransmissioninratmesentericarteriesviaGPR55.
TechnicalData
| M.Wt | 364.57 |
| Formula | C23H40O3 |
| Storage | Desiccateat-20°C |
| CASNumber | 222723-55-9 |
| PubChemID | 6483057 |
| InChIKey | CUJUUWXZAQHCNC-DOFZRALJSA-N |
| Smiles | CCCCCC=C/CC=C/C/C=CC/C=CCCCCOC(CO)CO |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml) |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight364.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.74mL | 13.71mL | 27.43mL |
| 5mM | 0.55mL | 2.74mL | 5.49mL |
| 10mM | 0.27mL | 1.37mL | 2.74mL |
| 50mM | 0.05mL | 0.27mL | 0.55mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.